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Avodart dutasteride dosage ranges and dosing schedules for men are presented in Table 2. There is no significant difference between dutasteride and placebo treatment groups in mean EOP score at endpoint. The safety of dutasteride in men with benign prostatic hyperplasia (BPH) or other types of benign prostatic hyperplasia is comparable with those treated finasteride. Dutasteride at 1, 2, or 5 mg/d was not different from finasteride in post-marketing experience men treated with BPH (Table 4). Table 4: Male Dutasteride Treatment Dosing Regimens, Mean (95% CI) Dutasteride 1 mg/m 2 5 (and 11 more...) n = 2918 641 536 (and 2 more...) Placebo (n = 1585) 1041) (and 2 more...) Age (years) 27.8 ± 9.9 28.6 9.3 31.3 9.7 Weight (kg) 80.3 ± 17.0 76.4 14.8 81.7 16.0 Height (cm) 181.3 ± 8.4 183.6 7.2 185.6 8.8 BMI (kg/m2) 27.7 ± 4.2 27.9 2.7 29.2 5.2 Eosinophilia (EU/L) 13.9 ± 3.2 13.5 2.8 2.4 Serum BPH (IU/L) 5.3 ± 1.3 5.0 0.99 6.1 1.6 Free androgen indexa 33.8 ± 5.0 35.5 4.9 31.2 5.3 FSH (mIU/mL) 1.9 ± 0.6 1.8 0.5 1.5 0.49 Testosterone (ng/dL) 21.3 ± 12.0 25.0 19.8 33.4 32.7 Prostate specific antigen (PSA) 0.6 ± 0.1 1.3 0.5 0.9 0.7 Estradiol (pg/mL) 988 ± 434 1147 447 1609 811 Total T (ng/dL) 4.96 ± 1.28 4.97 1.23 7.20 1.45 Estrogens (ng/mL) 10.6 ± 3.4 12.2 4.1 15.5 6.0 TSH (mIU/mL) 3.7 ± 1.2 4.0 1.36 4.7 1.6 Corticosteroids ()

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